Buffalo Bills at New England Patriots

The Bills have been dominated by the Patriots in recent years, but they will be looking for their second straight win in the series since the seasons of 1999 and 2000. Last year, they won at Gillette Stadium by 17-9, but quarterback Tom Brady only played half a game. Before the triumph of last season, Buffalo had 13 straight losses in Foxborough. New England is listed in the betting Odds with -5.5 to win this match and in the last five at home against Buffalo is 4-1 SU and 2-3 ATS.

Player to watch: Wide receiver Sammy Watkins will have to improve their numbers if you the Bills want to stay in contention in this game. In 2014, the rookie had just five receptions for 84 yards in the two games against the Pats.